Premarketing experience with rizatriptan among the 3700 patients with migraine who participated in premarketing clinical trials of maxalt, one patient was reported to have chest pain with possible ischemic ecg changes following a single dose of 10 mg.
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the efficacy of maxalt tablets 5 mg in patients aged 12 to 17 years was not established in a randomized placebo-controlled trial of 291 adolescent migraineurs see clinical studies .
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the bioavailability and cmax of rizatriptan were similar following administration of maxalt tablets and maxalt-mlt orally disintegrating tablets, but the rate of absorption is somewhat slower with maxalt-mlt, with tmax delayed by up to 0.
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