Methotrexate pneumonitis treatment

10 de mayo 2018 | Juan Luis Durán

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Patients starting methotrexate should be carefully evaluated for renal insufficiency, acute or chronic liver disease, significant alcohol intake or alcohol abuse, leukopenia low white blood cell counts , thrombocytopenia low platelet counts , or untreated folate deficiency.

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Some times infusion of alkaline fluid may be used with methotrexate treatment in order to decrease the risk of renal toxicity.

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The effectiveness of methotrexate on trophoblastic tissue has been well established and is derived from experience gained in using this agent in the treatment of hydatiform moles and choriocarcinomas.

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Methotrexate decreases the body s ability to break down and use folic acid.

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Sulfamethoxazole; trimethoprim, smx-tmp, cotrimoxazole moderate use of other folate antagonists, such as methotrexate, should be avoided during therapy with trimethoprim.

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rheumy added methotrexate soon after, but i have had to increase my weekly pills to 8.

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