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A total of 114 subjects were randomized to receive either combination treatment of copegus plus pegasys or pegasys monotherapy; subjects failing pegasys monotherapy at 24 weeks or later could receive open-label copegus plus pegasys.

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the recommended dose ranges between 800mg to 1400mg day depending on the other medicines you are using in combination with copegus.

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of the patients who did not demonstrate either undetectable hcv rna or at least a 2log 10 reduction from baseline in hcv rna titer by 12 weeks of pegasys and copegus combination therapy, 2 2 85 achieved an svr.

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in study nr15961, patients who were administered zidovudine in combination with pegasys copegus developed severe neutropenia anc less than 500 and severe anemia hemoglobin less than 8 g dl more frequently than similar patients not receiving zidovudine neutropenia 15 vs.

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the efficacy and safety of copegus in combination with peginterferon alfa-2a or interferon alfa-2a have not been sufficiently evaluated in patients under the age of 18 years.

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-ribavirin 200 mg oral tablet copegus should not be administered simultaneously or combined with any other aerosolized medications.


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