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Recommended dosage of colchicine depends on whether patient is receiving or has recently within 14 days received a moderate or potent cyp3a4 inhibitor or an inhibitor of the p-glycoprotein transport system see table 3 .
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Colchicine comes only in the tablet form.
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As of 2009, colcrys is the only brand of colchicine that has been approved by the fda.
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First symptoms of colchicine intoxication are gastrointestinal disturbances, such as abdominal cramps, diarrhea, pancytopenia and so on.
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myelosuppression, leukopenia, granulocytopenia, thrombocytopeniapancytopenia and aplastic anemia have been reported with colchicine used in therapeutic doses.